 | Will Smith
Captain Steve Hiller |
 | Bill Pullman
President Thomas J. Whitmore |
 | Jeff Goldblum
David Levinson |
 | Mary McDonnell
First Lady Marilyn Whitmore |
 | Judd Hirsch
Julius Levinson |
 | Robert Loggia
General William Gray,
Chairman Joint Chiefs |
 | Randy Quaid
Russell Casse |
 | Margaret Colin
Constance Spano,
White House Communications Director |
 | Vivica A. Fox
Jasmine Dubrow |
 | James Rebhorn
Albert Nimzicki,
Secretary of Defense |
 | Harvey Fierstein
Marty Gilbert |
 | Adam Baldwin
Major Mitchell |
 | Brent Spiner
Dr. Brakish Okun |
 | James Duval
Miguel Casse |
 | Lisa Jakub
Alicia Casse |
 | Giuseppe Andrews
Troy Casse |
 | Ross Bagley
Dylan Dubrow |
 | Bill Smitrovich
Lt. Colonel Watson |
 | Mae Whitman
Patricia Whitmore |
 | Harry Connick Jr.
Captain Jimmy "Raven" Wilder |
 | Kiersten Warren
Tiffany |
 | John Storey
Dr. Isaacs |
 | Frank Novak
Teddy |
 | Devon Gummersall
Philip |
 | Leland Orser
Tech / Medical Assistant #1 |
 | Mirron E. Willis
Presidential Aide |
 | Ross Lacy
Presidential Aide |
 | David Pressman
Alex, Presidential Aide |
 | Vivian Palermo
Tech / Medical Assistant #2 |
 | Raphael Sbarge
Captain, Chief Ground Controller |
 | Bobby Hosea
Major Danowitz (according to credits)
(Col. Harper according to what's onscreen) |
 | Dan Lauria
Commanding Officer, Space Command |
 | Steve Giannelli
Commander, USS Georgia
(listed in credits as Radar Technician) |
 | Carlos Lacamara
El Toro Radar Operator |
 | John Bennett Perry
Secret Service Agent |
| Troy Willis
Secret Service Agent |
 | Tim Kelleher
Senior Airman, Ground Controller |
 | Wayne Wilderson
Area 51 Technician |
 | Jay Acovone
Area 51 Gate Guard |
 | James Wong
SETI Technician #1 |
 | Thom Barry
SETI Technician #2 |
 | Jana Marie Hupp
SETI Technician #3 |
 | Matt Pashkow
Second Officer in Space Command
(Major Danowitz according to script) |
 | Robert Pine
Glenn Parness,
White House Chief of Staff |
 | Marisa Johnston
Co-Worker #2 (as Marisa Morell) |
 | Michael Winther
Co-Worker #3 |
 | Dexter Warren
Co-Worker #4 |
| Paul LeClair
Co-Worker #5 |
| Michael Vacca
Lieutenant Peterson |
 | David Chanel
Secret Service Agent |
 | John Capodice
Mario |
 | Greg Collins
Military Aide |
 | Derek Webster
Sky Crane Pilot |
 | Mark Fite
Marine Fighter Pilot |
| Eric Neal Newman
Pilot |
 | Levan Uchaneishvili
Russian Pilot |
 | Kristof Konrad
Russian Pilot |
 | Kevin Sifuentes
Tank Commander |
 | Elston Ridgle
Soldier Guarding Helicopter |
 | Randy Oglesby
Mike Dodge |
 | Jack Moore
Stoney Jackson |
 | Barry Del Sherman
Street Preacher |
 | Lyman Ward
Secret Service Agent |
 | Anthony Crivello
Lincoln |
| Richard Speight Jr.
Ed |
 | Barbara Beck
Monica Soloway |
 | Joe Fowler
Reporter |
| Andrew Warne
Reporter |
| Sharon Tay
Reporter |
| Peter J. Lucas
Russian Reporter (as Peter Jozef Lucas) |
| Yelena Danova
Russian Newscaster |
| Johnny Kim
Korean Newscaster (as Derek Kim) |
 | Vanessa J. Wells
Newscaster |
 | Gary W. Cruz
Carlos Ortiz, LA Newscaster |
 | Ron Pitts
Video Newscaster |
 | Wendy L. Walsh
Herself |
| Christine Devine
Video Newscaster |
 | Mark Thompson
Video Newscaster |
| Ernie Anastos
Rex Black, New York Newscaster |
 | Kevin Cooney
Commander-in-Chief,
US Atlantic Command |
 | Rance Howard
Chaplain |
 | Nelson Mashita
Japanese Technician |
 | Jeff Phillips
B-2 Pilot |
 | Sayed Badreya
Iraqi Pilot |
 | Adam Tomei
Sonarman, USS Georgia |
 | John Bradley
Lucas |
 | Kimberly Beck
Housewife |
 | Thomas F. Duffy
Lieutenant |
 | Andrew Keegan
Older Boy |
 | Jon Matthews
Thomson |
 | Jim Piddock
Reginald |
| Frederic W. Barnes
Himself (as Fred Barnes) |
 | Eleanor Clift
Herself |
 | Jerry Dunphy
Himself |
| Jack Germond
Himself |
 | Morton Kondracke
Himself |
 | John McLaughlin
Himself |
| Barry Nolan
Himself |
| George Putnam
Himself |
| Eric Michael Zee
Northridge Field Reporter |
 | Pat Skipper
Redneck |
| Carlos Lara
Farmer Kid |
| Mike Monteleone
Butler |
| Lee Strauss
Elvis Fanatic |
| Lisa Star
Woman on Roof |
 | Malcolm Danare
Intellectual on Roof |
| Arthur Brooks
Trucker on Roof |
| Michael Moertl
Thief |
| James J. Joyce
Master Chief Petty Officer |
| Joyce Cohen
Kim Peters |
 | Julie Moran
Herself - "Entertainment Tonight" Reporter |
| Robin Groth
Flagstaff News Anchor |
| Richard Pachorek
LAPD Helicopter Pilot |
 | Gary A. Hecker
Alien Vocal Effects (as Gary Hecker) |
 | Frank Welker
Special Vocal Effects |
| Jonathan Adler
Secret Service Agent (uncredited) |
 | Erick Avari
SETI Chief (uncredited) |
 | Greg Bronson
Police Officer at White House (uncredited) |
| Dean Devlin
Eagle 2 Pilot (uncredited) |
| Daren Dochterman
British News Translator (uncredited) |
 | Volker Engel
Man in Office (uncredited) |
 | Bob Friend
Himself - "Sky News" Anchorman (uncredited) |
| Jeffrey Gold
German Fighter Pilot (uncredited) |
| Michael Haddad
Trailer Trash (uncredited) |
| Lincoln D. Hiatt
Colin Barclay (uncredited) |
| Jonathan Khan
Pilot (uncredited) |
| Darin Mangan
Staff Sergeant (uncredited) |
 | Scott McKinley
Joint Chiefs of Staff (uncredited) |
| Bryan D. Moss
Israeli Fighter Pilot (uncredited) |
| Roy Newton
Pilot (uncredited) |
| Gary Pike
Helicopter Passenger (uncredited) |
| Darla Rae
Protestor - Omni Hotel (uncredited) |
 | Nectar Rose
Stripper (uncredited) |
| Bonnie Silco
Bride (uncredited) |
 | Tadao Tomomatsu
Big Hat Guy on Tower (uncredited) |
| Michael A. Valenzano
Young Pilot (uncredited) |
 | Tracey Walter
Area 51 Lab Technician (uncredited) |
 | James With
British Pilot (uncredited) |
| James Woodson
Pilot (uncredited) |
 | Dakota
Boomer |
 | Unknown 22068-2
AWACS Pilot |
 | Unknown 22068-3
Area 51 Gate Guard #2 |
 | Unknown 22068-4
Asian Pilot |
 | The White House
The White House |
 | World Trade Center
World Trade Center |